Chemically Altered

I'm reading Do Androids Dream of Electric Sheep.  Early in the story, it's revealed that people have the option to alter their moods using artificial methods.  People can dial in the mood that they want to amazingly specific degrees.  For example, the husband in the beginning of the story gets to choose his wife's mood for the day and chooses "pleased acknowledgement of husband's superior wisdom in all matters."  For those of you concerned about that choice, she had been feeling so bad that she had offered to choose "ecstatic sexual bliss."

The wife actually holds a strangely profound thought.  At one point, she decides to choose depression.  When asked why, she explains that it wrong to feel good when there are bad things going on around her.  Not showing the proper emotion when the situation requires it is a sociopathic behavior.

This is one of the reasons that I have avoided drugs, including tobacco and alcohol, for my entire life.  If I am happy, sad, pleased, or some other emotion because of a chemical created outside of myself, how do I know what I truly feel or who I truly am?  If I ingest something from outside myself to change the mood that I would naturally produce, am I not denying myself as well?

I understand the desire to feel better, but to do so artificially is a desire that is beyond me.